01 - Whisk buttermilk with salt, garlic powder, onion powder, cayenne, and black pepper in a large bowl until fully incorporated.
02 - Submerge chicken pieces in marinade, ensuring complete coverage. Cover and refrigerate for minimum 2 hours or overnight for optimal flavor penetration.
03 - Combine flour, paprika, salt, black pepper, cayenne, and baking powder in a separate bowl. Mix thoroughly to distribute spices evenly.
04 - Remove chicken from marinade, allowing excess liquid to drip off. Press each piece firmly into flour mixture, ensuring thick, even coating. Transfer to rack and rest for 10 minutes to set breading.
05 - Heat vegetable oil in deep fryer or heavy pot to 350°F.
06 - Lower chicken pieces into hot oil in batches, avoiding overcrowding. Fry for 12-15 minutes, turning occasionally, until golden brown and crisp with internal temperature reaching 165°F.
07 - Transfer fried chicken to wire rack or paper towels to drain. Let rest for 5 minutes before serving to allow juices to redistribute.